Dyke Davidoff Masson Syndrome (DDMS) with abdominal epilepsy, is a rare clinical condition. It is characterized by severe abdominal pain with seizures, facial asymmetry, contralateral hemiparesis, and mental retardation. Diagnosis is made clinically coupled with radiological features which include cerebral hemiatrophy with homolateral hypertrophy of the skull and sinuses along with abnormal EEG and response to antiepileptic drugs. Here we report a case of DDMS with abdominal epilepsy in a 10 year old male child who presented with recurrent episodes of severe abdominal pain followed by seizures, hemiparesis and mental retardation. CT and MRI showed hemiatrophy of right cerebral hemisphere.

Objective: The serine carbapenemase KPC (Klebsiella pneumoniae carbapenemase) has emerged as a beta-lactamase capable of inactivating carbapenem antibiotics. The emergence of carbapenem-resistant enterobacteria is therefore worrisome, since consequently the antimicrobial treatment options are very restricted. In the present study we have reported the presence of KPC ?-lactamase producing enterobacterial isolates from a tertiary referral hospital in north India. Methods: The isolates were subjected to phenotypic confirmatory test by boronic acid and clavulanic acid inhibition and presence of carbapenemase activity. They were further tested for PCR detection of blaKPC and the associated genetic component. Results: Three enterobacterial isolates were found to be phenotypically similar to that of KPC enzyme and genotypically showing positive results with primers specific for blaKPC gene were found to be located on integron. Conclusion: The findings indicate the need for continuous surveillance of this resistant determinant in this part of the world.

Triple-negative breast cancer refers to a specific subtype of breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or Her2/neu. About 12-17 % of ca breast have triple negative ca breast This subtype of breast cancer is clinically characterized as more aggressive and less responsive to standard treatment and associated with overall poorer prognosis. Chemotherapy is the choice of systemic therapy for triple-negative tumors. They are more susceptible to non-receptor mediated therapies than other tumors. A number of new strategies are currently being tested in clinical trials.

Variation of brachial plexus characterized by the absence of musculocutaneous nerve in right arm was found during routine dissection of a 54 year old male cadaver. After giving lateral pectoral nerve, rest of the lateral cord continued as lateral root of median nerve. An unusual branch was arising from lateral cord which crossed the axillary artery anteriorly and then divided into two branches. One of these branches joined ulnar nerve and other medial root of median nerve. All the muscles of front of arm were supplied by branches of median nerve. These variations are important for the anesthetists, surgeons, neurologists during surgery and for anatomists during dissection in the region of axilla.

Although India is in the grip of HIV/AIDS epidemic, not much information is available on socio-demographic and clinical aspects of people living with HIV/AIDS (PLWHA). The present study has been designed with the following objective. Objectives: To assess the socio-demographic and clinical profile of people living with HIV/AIDS (PLWHAs) in India. Material and methods: The study was carried among 251 HIV/AIDS positive persons attending the out-patients department at the antiretroviral treatment (ART) clinic of the HIV testing centers at three major govt. hospital of Delhi, India. All the patients, male and female in the age range of 20-65 years and willing to participate were included in this study during the period 2007-2009. Written as well as informed consent was obtained for each patient at the time of recruitment. The HIV status was analyzed by ELISA with further confirmation by western blot; CD4/CD8 counts were measured by a flow-cytometer. Statistical analysis was carried out using chi-square test in order to see the association between age groups for various psychological measures and for treatment responses of the participants receiving ART. Results: Majority of the patients (77.7%) were found to be young (40 years) and married (86.9 %). As high as 61.8% came from low socio-economic class and more than 93.6% acquired HIV transmission through heterosexual routes. A large proportion of these patients reported an extremely high level of anxiety, moderate level of stress and a borderline level of clinical depression. While some of the patients (28.3%) were well-adjusted with the ART, the rest of the patients reported difference in making adjustment with the treatment schedules. Conclusion: The study suggests that counselling and supportive therapy could play a pivotal role in controlling anxiety, stress, depression and rehabilitating people with HIV/AIDS. Thus, proper preventive intervention among general population and establishment of proper laboratory support is recommended.